Saints Row is a 2006 open world action-adventure video game for the Xbox 360. Developed by Volition, Inc. and published by THQ, Saints Row was released in North America on August 29, 2006, followed by an Australian release two days later and a European release on September 1, 2006. It was met with generally positive critical reception; reviewers noted its similarities with the Grand Theft Auto series, with some feeling that Saints Row improved Grand Theft Auto '​s open world formula. It is the first game in the Saints Row series.

Saints Row allows players to freely roam the play space and engage in missions at their leisure. Missions are unlocked by trading in "Respect" points, currency earned by completing mini-games, and are played through three story arcs each with the objective of overthrowing a rival gang. Saints Row is set in the fictional city Stilwater, modeled on Chicago, Detroit, Cleveland, and Baltimore. The player character becomes inadvertently involved in a gunfight between the three gangs fighting for control of Stilwater; Los Carnales, the Vice Kings, and the Westside Rollerz. He joins forces with the 3rd Street Saints gang, based out of the Saint's Row district, and works with the Saints to free Stilwater from gang control.